Respiratory physiotherapy can increase lower esophageal sphincter pressure in GERD patients
نویسندگان
چکیده
منابع مشابه
Pathophysiology of GERD: Lower Esophageal Sphincter Defects
44 INTRODUCTION T he most common cause of gastroesophageal reflux disease (GERD) is lower esophageal sphincter (LES) dysfunction. The LES is a 3–4 cm high-pressure zone of muscular activity in the distal esophagus. The LES is anatomically and histologically distinct from the esophageal body. Manometric and radiographic studies can be used to identify the LES. Intraluminal manometry can detect t...
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Up to 50% of patients with gastroesophageal reflux disease (GERD) still suffer from GERD symptoms despite proton pump inhibitor (PPI) therapy, indicating a need for new treatments. The lower esophageal sphincter (LES) plays a crucial role in maintaining the mechanical barrier necessary for prevention of gastric reflux. Transient LES relaxation (TLESR) is an important factor behind the occurrenc...
متن کاملLower esophageal sphincter pressure measurement under standardized inspiratory maneuveurs.
BACKGROUND Through rhythmic variations, the diaphragm influence lower esophageal sphincter (LES) pressure acting as an external sphincter. LES pressure recording is characterized by increased pressure in inspiration due to contraction of the diaphragmatic crura that involves the sphincter. AIM To describe a method of measuring LES pressure during standardized inspiratory maneuvers with increa...
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OBJECTIVE Ginger has been traditionally used to reduce intestinal gas and flatulence. The present study examined the effects of ginger on the esophagus and lower esophageal sphincter (LES) function by esophageal manometry. STUDY DESIGN A randomized controlled trial. SETTING Departments of Physiology and Medicine, Faculty of Medicine Siriraj Hospital. SUBJECTS Fourteen healthy young male v...
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We studied the effect of distal oesophageal acidification on lower oesophageal sphincter (LOS) pressure in normal human volunteers and in cats. The distal oesophagus was acidified by intraluminal injection of 0.1N HCl (pH 1.2). The LOS pressure was recorded by a sleeve device while pharyngeal and oesophageal pressures were monitored by nonperfused, water filled catheters. In normal human subjec...
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ژورنال
عنوان ژورنال: Respiratory Medicine
سال: 2012
ISSN: 0954-6111
DOI: 10.1016/j.rmed.2012.08.023